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butabarbital will lower the extent or effect of nicardipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.butabarbital will reduce the level or outcome of carvedilol by impacting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.butabarbital will lessen the extent or result of pimozide by affecting hepatic/int